NPR

Taste Buds Dull As People Gain Weight. Now Scientists Think They Know Why

Doctors have known that as people pack on the pounds, their sense of taste diminishes. New research in mice helps explain what's going on: Inflammation brought on by obesity may be killing taste buds.
A color-enhanced scanning electron micrograph of the surface of the human tongue. Taste buds are shown in purple. Doctors have known that as people pack on the pounds, their sense of taste diminishes. New research in mice suggests one reason why: Inflammation brought on by obesity may be killing taste buds.

In Robin Dando's lab, several mice chowed down on a specialized diet designed to make them as fat as possible. "I can say the mice are happy. They love this unhealthy diet, and pretty fast they get pretty overweight," says Dando, an assistant professor of food science at Cornell University.

But the mice were not long for this world. Eight weeks after they started their delicious nosh, they were euthanized and their tongues were excised for direct comparisonskinnier brethren.

You’re reading a preview, subscribe to read more.

More from NPR

NPR2 min read
Peloton Is Laying Off Workers And Replacing The CEO — Again
It's déjà vu for the luxury fitness company: Peloton is cutting about 400 more jobs, and its CEO is stepping down just two years after a major shakeup.
NPR7 min readAmerican Government
Trump Trial Coverage
The news media face a number of temptations while covering the criminal trial of former President Donald Trump, including dwelling on salacious details, overdramatizing insignificant moments, and getting distracted by out-of-court behaviors that have
NPR1 min readAmerican Government
FTC Bars Former Pioneer CEO In Exxon Mobil Deal, Saying He Colluded With OPEC
Exxon Mobil's $60 billion deal to buy Pioneer Natural Resources received federal clearance, but former Pioneer CEO Scott Sheffield was barred from joining the new company's board of directors.

Related Books & Audiobooks