Please visit answersincme.com/NSY860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in thoracic oncology discusses neoadjuvant systemic treatment of resectable non–small-cell lung cancer. Upon completion of this activity, participants should be better able to: Outline opportunities for improvement over the currently recommended neoadjuvant systemic regimens for patients with resectable NSCLC; Explain the clinical implications of emerging data evaluating chemo-immunotherapeutic approaches for the neoadjuvant treatment of resectable NSCLC; and Describe how to develop a personalized, evidence-based treatment plan for patients with resectable NSCLC.