Welcome to our four-episode series: Raising Awareness of Hepatorenal Syndrome Acute Kidney Injury (HRS-AKI). In episode one, our host Muhamad Nadeem Yousaf, MD, speaks with Danielle Adebayo, MD, and Florence Wong, MD, MBBS, FRCPC, to analyze the pathophysiology of HRS-AKI. They cover peripheral vasodilatation hypothesis shortcomings in HRS-AKI, vasoconstrictor systems, bacterial translocation, inflammation, renal dysfunction, and contributory factors like cholemic nephropathy and adrenal insufficiency, while also suggesting the potential of metabolomic studies for future insights.

Each episode of this series corresponds to a journal article from a September 2023 supplement of Clinical Gastroenterology and Hepatology (CGH), the official clinical practice journal of the American Gastroenterological Association, focusing on addressing knowledge gaps in HRS-AKI.

To read the related journal articles and claim CME for listening, visit agau.gastro.org.

This series is supported by an independent educational grant from Mallinckrodt