New research shows that HPV vaccination rates have increased, and interventions targeted to parents and health care professionals can improve rates. JAMA Pediatrics Editor in Chief Dimitri Christakis, MD, and JAMA Pediatrics Associate Editor Alison Galbraith, MD, discuss strategies to increase HPV vaccination with Melissa Gilkey, PhD, of the University of North Carolina's Gillings School of Global Public Health. Related Content: Multilevel Implementation Strategies for Adolescent Human Papillomavirus Vaccine Uptake Trends in HPV Vaccination Before Age 13 Years in the US National Immunization Survey–Teen