This full-length episode on the inpatient management of acute pancreatitis includes not only the admission framework, but also key clinical pearls on the background, pathophysiology, etiologies, presentation, diagnosis, treatment, and complications associated with the disease to help take your understanding to the next level!
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Timestamps

00:00:00 - Background and Epidemiology
00:01:13 - A Note on Chronic Pancreatitis
00:01:31 - Admission Checklist
00:03:49 - HPI Intake
00:04:33 - Physical Exam
00:05:20 - Etiology and Differential
00:06:20 - Plan - Work Up
00:07:30 - Plan - Treatment
00:09:31 - If You Remember Nothing Else
00:10:04 - Pearls - Pathophysiology
00:11:15 - Pearls - Etiology and Risk Factors
00:12:56 - Pearls - Presentation and Diagnosis
00:15:56 - Pearls - Treatment
00:18:08 - Pearls – Complications

Show Notes

Reviews

Acute Pancreatitis: A Review ⁠(JAMA, 2021)⁠
Acute Pancreatitis ⁠(NEJM, 2016)

Trials

WATERFALL Trial - Aggressive (20 ml/kg bolus + 3 ml/kg/hr) vs Non-Aggressive (10 ml/kg bolus + 1.5 ml/kg/hr) fluid resuscitation in acute pancreatitis - fluid overload resulted in 20.5% vs 6.3% of patients but no difference in the development of moderately severe or severe pancreatitis ⁠(NEJM, 2022)

Other Literature

Enteral versus parenteral nutrition for acute pancreatitis ⁠(Cochrane, 2010)⁠
A Critical Evaluation of Laboratory Tests in Acute Pancreatitis ⁠(Am J Gastroenterol, 2002)

Blogs and Summaries

Clinical Problem Solvers - Acute Pancreatitis Illness Script
Internet Book of Critical Care - Pancreatitis
Radiopaedia - Imaging Findings in Acute Pancreatitis
Pathway Guidelines Summary - Acute Pancreatitis