Vasomotor symptoms are common during menopause and may have substantial negative effects on quality of life. JAMA Senior Editor Linda Brubaker, MD, MS, discusses nonhormonal therapies for menopausal vasomotor symptoms with Susan D. Reed, MD, MPH, MS, professor emeritus at the University of Washington and president and CEO of The North American Menopause Society. Related Content: Nonhormonal Therapies for Menopausal Vasomotor Symptoms