"A lot of us have had patients with PRP who went on a biologic and they cleared quite rapidly and were very happy afterwards."Dr Patrick Fleming joins Kirk Barber, JCMS editor-in-chief, to discuss his article in the Jan/Feb 2020 issue of the journal, titled: “Use of Biologics in Pityriasis Rubra Pilaris Refractory to First-Line Systemic Therapy: A Systematic Review.“Dr Patrick Fleming talks about how there has been an increasing number of studies reporting the successful use of biologictherapy in patients with PRP, a relatively rare skin disease, however the data on the efficacy and safety is limited. His objective, along with his colleagues, was to evaluate the existing evidence for utilizing biologics, whether alone or in combination with established systemic therapies, in patients with treatment-resistant pityriasis rubra pilaris.Theme music is by Lee Rosevere.JCMS Author Interviews is produced for the Canadian Dermatology Association by David McGuffin of Explore Podcast Productions in Ottawa. davidrcmcguffin@gmail.com