Nick talks to medicinal chemist Dr. David Nichols, who has spent decades studying the chemistry and pharmacology of psychedelics. Dr. Nichols shared his knowledge of psychedelic tryptamines, including LSD and DMT, as well as phenethylamines, such as mescaline and MDMA. He also discussed his relationship with the late Dr. Alexander "Sasha" Shulgin, and how his thoughts companies trying to make non-hallucinogenic drugs derived from psychedelics.SUPPORT M&M:Sign up for the free weekly Mind & Matter newsletter:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Learn more about our podcast sponsor, Dosist[https://dosist.com]Support the showSign up for the free weekly Mind & Matter newsletter:[https://mindandmatter.substack.com/?sort=top]Learn how you can further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Become a Premium Subscriber to access full content library, including full premium episodes:[https://mindandmatter.substack.com/subscribe?utm_source=menu&simple=true&next=https%3A%2F%2Fmindandmatter.substack.com%2F]Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for $50 off:[https://www.lumen.me/shop?fid=8731&utm_source=influencer&utm_medium=influencer&discount=MIND]