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Estradiol Complicates Everything: Toxicology across the Gender Spectrum

Estradiol Complicates Everything: Toxicology across the Gender Spectrum

FromAdverse Reactions


Estradiol Complicates Everything: Toxicology across the Gender Spectrum

FromAdverse Reactions

ratings:
Length:
29 minutes
Released:
Jun 29, 2023
Format:
Podcast episode

Description

When it comes to hormones, everyone has them all, but their levels are where things get interesting. How chemicals affect estrogen signaling in the brain is the research focus of Troy Roepke, Rutgers, who talks to co-hosts Anne Chappelle and David Faulkner about how gender is not easily defined biologically, what it is like to be a “fabulously queer” professor, and how science can better serve the LGBTQ+ and other marginalized communities.About the GuestTroy Roepke, PhD, is an Associate Professor in the Rutgers School of Environmental and Biological Sciences Department of Animal Sciences, where their research goal is for a greater understanding of the interaction between novel steroid (estrogen) signaling pathways, neuroendocrine functions, maternal and adult diets, and endocrine-disrupting chemicals on homeostatic functions controlled by the hypothalamus, as well as the long-term consequences of maternal exposures to low doses of endocrine-disrupting chemicals in model species and how these maternal exposures may affect normal adult offspring physiological functions.In addition to their teaching and lab duties, Dr. Roepke serves as Associate Dean of Diversity, Equity, and Inclusion for the Rutgers School of Environmental and Biological Sciences. Dr. Roepke believes one of the most important aspects of being an openly queer professor is to create a lab environment that is supportive of all historically excluded students and trainees, especially LGBTQ+ students. They believe that great science happens when one creates a supportive, diverse, and inclusive environment that prioritizes teamwork, positivity, and respect wherein each team member feels welcomed and encouraged to bring their true authentic selves to the lab.Dr. Roepke received a doctorate in physiology with a designated emphasis in reproductive biology from the University of California Davis in 2005. Their postdoctoral training was at Oregon Health & Science University, studying the neuroendocrinology of estrogens from 2005 to 2011 where they were the recipient of a K99/R00 Pathways to Independence Award from the National Institute of Diabetes and Digestive and Kidney Diseases to study how endocrine disruptors influence metabolism. 
Released:
Jun 29, 2023
Format:
Podcast episode

Titles in the series (23)

An interview podcast bringing you the people and stories behind the science of how biological, physical, and chemical agents may cause adverse reactions to public, animal, and environmental health. This podcast is presented by the Society of Toxicology (SOT) and hosted by SOT members Anne Chappelle and David Faulkner.About AnneAfter graduating from the University of Delaware with a BS in biology in 1991, Anne Chappelle accidentally found her calling when she worked a gap year in an industrial toxicology laboratory. As it turned out, toxicology was the perfect marriage of protecting both human health and the environment. She then went on to receive her PhD in pharmacology and toxicology from the (now) University of the Sciences in Philadelphia in 1997, focusing on upper respiratory tract toxicity.For the last 20+ years, as a toxicologist and risk assessment expert for the chemical industry, Anne has been thrilled to not work in a laboratory anymore. Along the way, she has added a few more titles: spouse; DABT; Principal of Chappelle Toxicology Consulting, LLC; occasional blogger at My Toxic Life; and most life changing (and expensive): Mom. She is thrilled to be partnered with David to add podcast co-host to the list because it gives her the opportunity to “channel my inner Terry Gross.”About DavidDavid Faulkner’s interest in science started at age five with a few Bill Nye the Science Guy VHS tapes and hasn’t diminished since. A lifelong artist and science fan, David has worked in nearly every mass communication medium to share his love of science with the world. Now, as an early career toxicologist, David is living out his dream of co-hosting a science podcast! With a budget! And a producer! And super cool guests! And an awesome co-host! David thinks Bill would be proud.David attended the University of Michigan, where he completed a BS in microbiology, a BA in English language (emphasis in creative writing), and an MPH in environmental health sciences, and the University of California Berkeley, where he completed a PhD in molecular toxicology under the supervision of Dr. Chris Vulpe. He has held postdoctoral appointments at the Berkeley Center for Green Chemistry and the Lawrence Berkeley National Laboratory and just started a new position as a toxicological risk assessor. He also is a full-time parent to two adorable purple velvet plants: Planthony Bourdain and Marie Planthoinette.DisclaimerThe viewpoints and information presented in Adverse Reactions represent those of the participating individuals. Although the Society of Toxicology holds the copyright to the production, it does not vet or review the information presented nor does presenting and distributing the Adverse Reactions podcast represent any proposal or endorsement of any position by the Society.