Contributor: Chris Holmes MD Educational Pearls: “It’s a poor sort of memory that only works backwards” - Transient Global Amnesia A syndrome with sudden retrograde memory loss in which patients cannot retain new information Characterized by perseveration in frequent intervals Typically improves within hours MRI is normal initially Alice In Wonderland Syndrome A disorder in which patients experience distortions in their visual perceptions Most often characterized by micropsia and/or macropsia Other symptoms may include illusory movement or wavy lines Alice in Wonderland as a metaphor for birth Traveling down the rabbit hole is conception Alice getting bigger in a confined space is pregnancy Drinking potions is amniotic fluid Escaping to explore a scary world is childbirth References 1. Blom JD. Alice in wonderland syndrome. Alice Wonderl Syndr. 2019;(June):1-221. doi:10.1007/978-3-030-18609-8 2. Ropper M.D. AH. Transient Global Amnesia. N Engl J Med. 2023;(388):635-640. doi:10.1056/NEJMra2213867 Summarized by Jorge Chalit, OMSII | Edited by Meg Joyce & Jorge Chalit, OMSII