In this conversation, Daniel Belkin and Mitch Belkin speak with Joel Topf, MD, about contrast-associated nephropathy. We discuss Acute Kidney Injury (AKI), the value of creatinine as a marker for AKI, how to evaluate volume status, the evidence around contrast-induced/contrast-associated nephropathy, recommendations on fluids to prevent AKI in patients with Chronic Kidney Disease, and comparing venous and arterial contrast with respect to the risk of AKI.Who is Joel Topf?Dr. Topf is a clinical nephrologist in Detroit, who is a partner and medical director at St Clair Nephrology and an assistant professor at Oakland University William Beaumont School of Medicine. He is the co-creator of NephMadness and NephJC. He hosts multiple podcasts, blogs at pbfluids.com, and tweets @Kidney_boy. References: Joel Topf’s Blog Twitter: @Kidney_BoyJoel Topf - Grand Rounds Presentation on Contrast NephropathyThe PRESERVE trialN-Acetylcysteine and Contrast-Induced Nephropathy in Primary AngioplastyPrevention of Contrast-Induced Nephropathy With Sodium BicarbonateCraig Brater 1998 - NEJM review on DiureticsChlorthalidone for Hypertension in Advanced Chronic Kidney DiseaseEffect of Salt Substitution on Cardiovascular Events and Death______________________What is the External Medicine Podcast?The External Medicine Podcast explores some of the most exciting ideas in medicine. Co-hosted by Daniel Belkin, MD, and Mitch Belkin, MD.Support the showFollow us at @ExMedPod Subscribe to our Youtube channelConsider supporting us on Patreon