In this episode, Drs Hessels and Larson describe how a positive patient safety climate contributes to improved adherence to infection prevention and control practices. This study produced findings not previously published thus advancing the state of the science in patient and occupational health and safety and infection prevention and control. These include identifying modifiable features of the safety climate and key organizational characteristics associated with better outcomes. With special guests: Amanda Hessels PhD RN CIC Assistant Professor at Columbia University, School of Nursing and a Nurse Scientist at Hackensack Meridian Health Elaine Larson, RN, PhD, FAAN, CIC Professor Emerita, School of Nursing and Department of Epidemiology, Columbia University, and Senior Scholar in Residence, New York Academy of Medicine