In this collaborative episode with JPGN, Drs. Peter Lu and Jason Silverman talk to Dr. Jim Squires, the first author of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure published recently in JPGN. Although this is a complex syndrome and topic, the discussion highlights important principles to consider and an initial approach to patients with this condition. Dr. Squires is Associate Director of Hepatology and Fellowship Director for Pediatric Transplant Hepatology at the University of Pittsburgh.Want to learn more about Pediatric Acute Liver Failure (PALF)? Join us on April 14 at 7 pm EST for the FIRST #PedsGIChat! Follow the hashtag and @PedsGIChat for a great discussion with Dr. Mohit Kehar on this topic, and keep following for news about future chats as well! Our thanks to the NASPGHAN Technology Committee for setting this up!This episode is eligible for CME credit!  Once you have listened to the episode, click this link to claim your credit.  Credit is available to NASPGHAN members (if you are not a member, you should probably sign up).  And thank you to the NASPGHAN Professional Education Committee for their review!Learning Objectives:Understand the initial assessment and triage of a patient with suspected PALF.Understand the diagnostic evaluation of infants and children with PALF.Review the ongoing monitoring of patients with PALF to assess for complications.Links:NASPGHAN Position Paper on the Diagnosis and Management of Pediatric Acute Liver FailureFollow the conversation on Twitter!JPGN Fellow Reviewer Program application formAs always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Produced by: Jason SilvermanSupport the showAs always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Follow us on Twitter, Facebook and Instagram for all the latest news and upcoming episodes!