In this episode we talk to Dr Lieke Koggel who is a PhD candidate in gastroenterology at the Department of Gastroenterology and Hepatology, Radboud Institute for Health Sciences, The Netherlands.Paper: Predictors for inappropriate proton pump inhibitor use: observational study in primary carehttps://doi.org/10.3399/BJGP.2022.0178While overuse of proton pump inhibitors (PPI) is a common issue worldwide, predictors for this remain insufficiently known. This observational study using real-world primary care data identified older age and non-selective NSAID use as most predictive for inappropriate PPI use. The study also showed that unnecessarily continued PPI therapy is common in patients using PPI therapy for dyspepsia or as ulcer prophylaxis. Future initiatives on reducing inappropriate PPI use should target these patient groups.