In this episode of Karger’s Fast Facts Podcast, the first in a three-part special on hyperkalemia and chronic kidney diseases, we talk with Adam Whaley-Connell, Professor of Medicine at the University of Missouri School of Medicine and Harry S Truman VA Hospital, USA. Dr Whaley-Connell joins us to talk about the molecular basis of how hyperkalemia happens, how it presents in patients, and what risks it poses to long term health. To learn more about Dr Whaley-Connell and the work of his team visit Adam Whaley-Connell, DO - MU Health Care. Dr Whaley-Connell has also recently co-developed a freely available Karger interactive e-learning program to educate healthcare professionals on chronic kidney diseases and hyperkalemia, entitled – Hyperkalemia: Overcoming the Achilles' Heel of Guideline-Directed Therapy in CKD from Diabetes For more podcast episodes from Karger visit  www.karger.com/podcasts