This episode features recent updates presented at the 2022 European Society for Medical Oncology (ESMO) Congress in Paris, France. SOLO1 study survival data, PAOLA data, and information about novel, early-phase drugs and their practice implications are reviewed by three speaker experts. This is an educational resource produced through collaboration between the Society of Gynecologic Oncology (SGO) and the Cancer Association of Community Cancer Centers (ACCC).