Alendronate is a bisphosphonate that is used in the management of osteoporosis.



In this episode, I discuss osteonecrosis risk and what are some of the risk factors that may increase the chances of this very rare adverse effect.



Binding interactions are so critical with alendronate. They can essentially make the drug useless.



Esophageal irritation and ulceration is one of the possible complications with the use of alendronate.