In this podcast, Dr. Jonathan Fuller and Dr. Jeremy Simon discuss disease as a concept. Are diseases part of the natural world, like electrons and photons, or created by humans and their perceptions and interests, like constellations or countries?Dr. Fuller is a philosophy of medicine postdoctoral fellow and graduating medical student at the University of Toronto. Dr. Simon is an emergency physician and a bioethicist at Columbia University in New York city.For more philosophical discussions related to medicine, visit www.philosophersonmedicine.comFull humanities article: www.cmaj.ca/lookup/doi/10.1503/cmaj.181629-----------------------------------Subscribe to CMAJ Podcasts on Apple Podcasts, iTunes, Google Play, Stitcher, Overcast, Instacast, or your favourite podcast app. You can also follow us directly on our SoundCloud page or you can visit www.cmaj.ca/page/multimedia/podcasts.