The word of the Lord to St. Ephraim: "Ecumenism has a spirit of wickedness and is dominated by unclean spirits."  
Demetrios Tselengidis, professor of dogmatic theology at the University of Thessaloniki, writes of his experiences with St. Ephraim of Katounakia:   
So I asked him on the matter in hand - if he could tell me what kind of thing Ecumenism is. He replied outright and without any difficulty:  
"This question, my child, had also been posed by someone else, some time before you. I myself have been up here on these rocks for forty years... I have even forgotten my Greek (note that he had completed Middle School) and as such, I haven’t preoccupied myself with that issue. But, because I had to reply – seeing that I had been asked about it, and since I had no knowledge of the matter - I went to my cell and prayed, asking Christ to inform me what Ecumenism is. I received His reply, which was that Ecumenism has a spirit of wickedness and is dominated by unclean spirits."  
So I asked him exactly how that was verified. He replied that "after praying, my cell became filled with an unbearable stench, which caused my soul to feel asphyxiated; I couldn’t breathe spiritually."  
I asked him if that had been an extraordinary event for him, or if that was the way that Christ responds in analogous cases, and he assured me that "in all the cases that are involved with sorcery, with unclean spirits, that is the state in which He enlightens me. Sometimes there is a spoken response, but in the present case, that was His answer and I have the absolute certainty that Ecumenism does not have the Holy Spirit, but the unclean spirit."  
Read the full account from Professor Tselengidis here: https://orthochristian.com/93492.html 
Photo in the thumbnail is of an Ecumenical Prayer gathering at Sts. Peter and Paul’s Coptic Church in Cairo, Egypt in 2017. Featured at this gathering was Patriarch Theodoros II of Alexandria, Pope Francis of Rome, Coptic Pope Tawadros II, Ecumenical Patriarch Bartholomew and more: https://www.ecupatria.org/2017/05/01/ecumenical-prayer-in-egypt-for-peace-and-unity/ 
Many canons condemn prayer with the heterodox, among other expressions of the heresy of ecumenism. Apostolic Canon 45: “Let a bishop, presbyter, or deacon, who has only prayed with heretics, be excommunicated: but if he has permitted them to perform any clerical office, let him be deposed.”  
A useful starting point to understand the heresy of ecumenism is the 1983 ROCOR condemnation of ecumenism, added to the Synodikon read on the Sunday of Orthodox in Great Lent: "Those who attack the Church of Christ by teaching that Christ’s Church is divided into so-called “branches” which differ in doctrine and way of life, or that the Church does not exist visibly, but will be formed in the future when all “branches” or sects or denominations, and even religions will be united into one body; and who do not distinguish the priesthood and mysteries of the Church from those of the heretics, but say that the baptism and eucharist of heretics is effectual for salvation; therefore, to those who knowingly have communion with these aforementioned heretics or who advocate, disseminate, or defend their new heresy of Ecumenism under the pretext of brotherly love or the supposed unification of separated Christians, Anathema!"  
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