In this special bonus episode, Adam Rutherford explores a different aspect of gene therapy - how do you actually make one? Expert guests discuss the highly complex task of scaling-up manufacturing from the small amounts needed for research, to creating batches big enough for clinical and commercial scale. And once that hurdle has been cleared, how do they address the additional challenge of storing and transporting the medicine at ultra-low temperatures?Featuring guests:Bert Bruce, Regional President, North America, Rare Disease, PfizerBob Smith, Senior Vice President, Global Gene Therapy Business, Rare Disease, Pfizer Sonal Bhatia, Chief Medical Officer, Rare Disease, Pfizer