A discussion with Drs. Nancy Everds, Nianyu Li and Katherine Sprugel from Amgen in Seattle, Washington about the article “Unexpected thrombocytopenia and anemia in cynomolgus monkeys induced by a therapeutic human monoclonal antibody”.  This manuscript won the journal’s best paper award in 2013 and describes a study that is a cautionary tale for those investigating/testing monoclonal antibodies.
 
Click here to read the full article.