Sally Hargreaves discusses highlights from the March issue: a review about the emergence of multidrug-resistant Enterobacteriaceae that produce extended-spectrum β-lactamases (ESBLs) within the community setting, an important cause of urinary-tract infections. Also discussed is a feature and the editorial about human papilloma (HPV) vaccination programmes, and the review about Whipple's disease, a condition which is both rare and poorly understood.