Alain Tremblay, MD, and editorialist David E. Ost, MD, FCCP, joined CHEST Podcast Editor, D. Kyle Hogarth, MD, FCCP, to discuss the research by multi-center Canadian study by Tremblay et al that evaluated how well autofluorescence bronchochoscopy (AFB) detected high-grade lesions in patients at risk for lung cancer. Their study determined that too few CT occult cancers were detected to justify its addition into a lung cancer screening program.