Jess is finally joined by our showbiz glamour muse... star of stage, screen and radio... Ms. Sandra Bernhard! Sandy reflects on her iconic Letterman appearances, her friendship with Madonna, playing Nancy on Roseanne and crafting her one-woman shows. Sandra also shares about her relationship with her girlfriend Sara of 20 years, ultimately not having a baby with Isaac Mizrahi, and Sara's impact on their daughter. Finally, we chat about how she infuses her life with Jewish spirituality and astrology. IG: @jessxnyc & @hottakesdeepdives