Mitch Rothholz, R.Ph., MBA (Washington, D.C.), a pharmacist currently serving as Chief of Staff for the American Pharmacists Association, discusses how the SMARxT Disposal campaign, in partnership with the U.S. Fish and Wildlife Service, addresses the problems associated with unused and expired medication waste. The discovery of pharmaceutical compounds in surface, ground and drinking waters has raised concern about the potential adverse environmental consequences these contaminants could have on wildlife and humans alike. For additional information, please visit www.pharmacist.com. Second guest, Lark Weller (St. Paul, MN), Community Planner with the Mississippi National River and Recreation Area, discusses water quality as it pertains to the great Mississippi River. For the human population, the river supplies drinking water, proper water levels for transportation and adequate flows for flushing away waste (Part 2). For additional information, please visit www.nps.gov/miss.