Dr. Charlie Wykoff describes the treat-and-extend (TREX) approach for the treatment of wet AMD. He then explains the study design and the 3-year results of the TREX-AMD trial. The full reference of the article is: Wykoff, C. C., Ou, W. C., Croft, D. E., Payne, J. F., Brown, D. M., Clark, W. L., . . . Group, T.-A. S. (2017). Neovascular age-related macular degeneration management in the third year: final results from the TREX-AMD randomised trial. Br J Ophthalmol. doi:10.1136/bjophthalmol-2017-310822 Please leave your comments in the iTunes show description or email to: theretinachannel@gmail.com