Three key Chiefs went down, as did a pair of Steelers wideouts and Marlon Mack. How should that affect your waiver-wire moves this week? Derrius Guice returned and might offer some help down the stretch. We'll look into him, some fringe QB starters and the 49ers offense on whole. It's also getting into time to set up our defenses for weeks ahead -- including the fantasy playoffs.​​Here's the rundown:Injuries and pickups ... 1:52Derrius Guice's return ... 18:06QB outlooks ... 22:44Getting defensive ... 35:30​Check our updated Rest of the Way rankings along with our Week 12 projections.