Did you know that the majority of people colonized with H pylori acquire it during infancy, and in the vast majority of cases infection is asymptomatic? Today we talk about the pathophysiology, history/exam, investigations and management of the world's most common infection- H. pylori! Written by Dr. Sama Anvari (internal medicine resident) and reviewed by Dr. Eric Greenwald (gastroenterologist) and Dr. John Neary (General Internist). Infographic by  Lucy Lan (Medical Student)