It is widely accepted that many autistic children and adults may have difficulties feeling comfortable in social interaction and social relationships given neurotypical expectations. Non-autistic people also may also feel uncomfortable and may have difficulty adjusting their style of communication and social interaction to support successful social engagement. Dave and Barry discuss these issues from a neurotypical and autistic perspective, looking, in part, through the lens of cultural differences in autistic and neurotypical conventions, while acknowledging the great individual variations in across individual people.