Multiple sclerosis often causes nerve pain with burning and pins-needles sensations, and spasticity associated with muscle tightness and cramping. The specific role of medical marijuana components including THC and CBD in MS in alleviating these MS symptoms addressed. Information regarding which MS patients are more likely to benefit from cannabis are reviewed in depth. Risks and concerns of cannabis use in MS addressed. All federal, state and local laws should always be followed. Barry Singer, MD, Director of The MS Center for Innovations in Care, interviews: Allen Bowling, M.D., Ph.D. , MS neurologist at the Colorado Neurological Institute Jacob Sosnoff, Ph.D., Associate Professor in Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign  To learn more, mslivingwell.org. To share your story, check out ICanWithMS.org.