The Anthropocene is characterized by exponential global change driven by human activity. But humans have been impacting the planet since the very earliest days when we first appeared on the evolutionary tree. In fact, one of the longest running debates in paleontology centers on homo sapiens’ role in wiping out North America's enormous land animals, known as megafauna. In this interview with paleontologist Liz Hadly, we talk about what life looked like in the Pleistocene, the pattern of human dispersal around the globe, and new scientific techniques that allow us to understand how ecosystems respond to perturbations, like the arrival of early humans. Generation Anthropocene is supported by the Stanford School of Earth, Energy & Environmental Sciences and by Worldview Stanford.