Professor Peter McCulloch, Dr Lauren Morgan and Ms Lorna Flynn discuss patient safety and the work of the Quality, Reliability, Safety and Teamwork Unit (QRSTU). Dr Morgan is Lecturer and Researcher in Human Factors, Ms Flynn is a Human Factors Research Assistant, and Professor McCulloch is Professor of Surgical Science and Practice, and head of the QRSTU at the Nuffield Department of Surgical Sciences, University of Oxford.