Researchers want to invent the technologies of the future, but there are plenty of chemical questions lurking in the past. In this episode of Stereo Chemistry, C&EN assistant editor Gina Vitale joins host Kerri Jansen to explore the centuries-old secrets and nagging mysteries that keep science historians up at night—and how these researchers go about solving them. A script and additional resources are available at bit.ly/3qGGHg5. Sign up for C&EN’s Grad Student Survival Guide at cenm.ag/gradsurvivalguide. Image credit: Marjolijn Bol/Lawrence Principe/John Haldon