David Krantz and I talk about how genetics affect the metabolism of cannabis (nutrigenomics) and the resulting impact of cannabis use on our epigenetic health. Furthermore, we reach into a discussion on how the same framework of understanding applies to our metabolism of psychedelics and the potential future of a genome-specific screening program for psychedelic-assisted psychotherapy. --LINKS-- For links to David's work, full show notes, and to watch this episode in video, head to Https://bit.ly/ATTMind111 **Full Topics Breakdown Below   --- SUPPORT THIS PODCAST —  Patreon: https://patreon.com/jameswjesso Donations: https://www.paypal.me/JWJesso Merchandise: https://www.jameswjesso.com/shop/ More options: https://www.jameswjesso.com/support/   Sponsor: FORMULA Nootropics https://www.jameswjesso.com/formula Use promo code "jesso" to get 20% off your first order.   Newsletter: https://www.jameswjesso.com/newsletter ------------- Episode Breakdown a general rundown of nutritional genomics and its application in understanding biology the profound health issues David faced that brought him into nutritional genomics (special note about the value of understanding polyvagal theory) the failure of the pre-packed dietary approach, be it veganism, paleo, or low-carb the endocannabinoid system the genetic differences of cannabis metabolism between different people why some people can “smoke weed every day” and make millions, and others can’t get off the couch how cannabis effects working memory differently in different genetic predispositions in each people based on baseline dopamine levels how our brain hides from itself the phenomena of “used to smoke all the time without issues then all of a sudden cannabis creates anxiety and paranoia” epigenetics and how cannabis changes how our genes express the genetic variant that increases the chances of developing cannabis-induced psychosis genetic profiling as a screening platform to understand what medical intervention would be most helpful for specific people the institutional complications that might prevent the introduction of genetic-specific medical care into the medical infrastructure how these ideas fit inside the modern context of the climate crisis how do genetic profiles influence dose-response differences with psychedelics speculating on the long term epigenetic impact of psilocybin use speculating on the long term epigenetic impact of therapeutic/healing work ---------- *** Big thanks to my patrons on Pateron for helping keep this podcast alive! Especially, Thomas & Melanie H, Clea S, Steven B, James R, Dean H, Joe A, Andy D, Stephen B, Ian C, David W, Don J, Yvett FC, Ann-Madeleine, Dima B, Chuck W & Cornelius Phlegmbottom ---------     --- SUPPORT THIS PODCAST —  Patreon: https://patreon.com/jameswjesso Donations: https://www.paypal.me/JWJesso Merchandise: https://www.jameswjesso.com/shop/ More options: https://www.jameswjesso.com/support/   Sponsor: FORMULA Nootropics https://www.jameswjesso.com/formula Use promo code "jesso" to get 20% off your first order.   Newsletter: https://www.jameswjesso.com/newsletter   --- BOOKS —    Decomposing The Shadow: https://www.jameswjesso.com/decomposing-the-shadow/ The True Light Of Darkness: https://www.jameswjesso.com/true-light-darkness/   --- LINKS —    Website: https://www.jameswjesso.com/ Speaking Tour: https://www.jameswjesso.com/events/ Podcast: https://www.jameswjesso.com/podcast/ Twitter: https://twitter.com/jameswjesso Instagram: https://www.instagram.com/attmindpodcast/ Facebook: https://www.facebook.com/jameswjesso   --- PRODUCTS —    Art: https://www.jameswjesso.com/product-category/art/ Teeshirts: https://www.jameswjesso.com/product-category/clothing/ Lectures: https://www.jameswjesso.com/product/psychedelics-ritualistic-suffering-and-the-meaning-of-life-lecture/