The Mountaineer football team will try to earn its second victory over a nationally ranked team on Saturday when No. 22 Iowa State visits Mountaineer Field. Neal Brown's squad, played its most complete game of the season last Saturday at TCU, but the Cyclones offer a much stiffer challenge. In six seasons, Coach Matt Campbell has successfully built Iowa State into a contender for the conference championship. On this episode, Brad, Hoppy and Tony give their thoughts on what it will take for the Mountaineers to emerge victorious. Do the Cyclones have any weaknesses? Will WVU be able to score against the Big 12's stingiest defense that's allowing just 17 points per game? Those questions and details of a very special in-game contest comes your way on the 324th episode of Three Guys Before Game.