Fibromyalgia patients typically present with chronic, widespread body pain and almost always have accompanying comorbid symptoms such as fatigue, memory difficulties, and sleep and mood difficulties.

Physical examination is typically normal but there is often diffuse tenderness.

Daniel Clauw, Professor of Medicine, Division of Rheumatology, University of Michigan Health System, Ann Arbor, gives us a clinical overview of the condition.

For more on fibromyalgia, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/187

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