(0:40) Welcome
Welcome back to The Paleo View listeners!
Stacy is home and is so excited to jump into this week's very science-y topic!
Snuggling her pets and sleeping in her own bed, Stacy is so happy
Stacy also shared an update on a family that she visited with while in Texas
Their daughter has alopecia and her hair is starting to grow back after following an AIP approach and working with her family to heal her body
Sarah shared her feelings on how significant this is and what this specific case shows us about the autoimmune protocol


This week's show sponsor is Just Thrive probiotics
Both Stacy and Sarah's family uses this product
Get 15% off with code PALEOVIEW15
Visit: https://thriveprobiotic.com/thepaleoview



(11:13) The Study that Sparked the Discussion
Recently, ahuman study was publishedlooking at how long-term adherence to a Paleo diet affects the gut microbiota and TMAO
Mainstream news picked it up the day it was published
Using headlines like, "Study linking Paleo diet to increased heart disease risk strengthens diet industry concerns"

There are a few physician-focused websites that publish news to keep doctors up to date on the medical literature
The headline was, "Paleo diet increases the risk for heart disease"

Sarah's inbox and The Paleo View's inbox was flooded with questions
It is common in these situations for mainstream media to pick up on any anti-fad diet study
The standard response from our community is to find some reason why this study is irrelevant


TMAO is often linked with red meat consumption
It is thought to be one of the mechanisms behind the link between increased cancer risk and increased cardiovascular disease risk and high red meat consumption

The reason why Sarah wants to dedicate an entire episode to this study is that it was very well done
It has some results that we need to pay attention to
Sarah doesn't see this study as a nail in the coffin on the Paleo diet
Instead, Sarah sees this as a very serious warning about a very particular type of implementation of Paleo
We need to make sure we are incorporating all the key principles of Paleo, instead of combining Paleo with other dietary approaches


This study shows us that there are problems with the longterm implementation of a low carb Paleo diet
Really what it is telling us is that root vegetables and fruit are awesome

The study was performed in Australia and they took people who self-reported following the Paleo diet for over a year
The controls were following the national dietary recommendations of Australia
These are similar to the recommendations made by the USDA/MyPlate

Within the Paleo group, they further divided them into two subgroups
The people who followed Paleo very strictly were called strict Paleo
The other group was called pseudo-Paleo
These people were consuming about one serving of grains or dairy per day
In the real world, most of us who have been following Paleo for a longtime fall closer to that pseudo-Paleo group
Strict Paleo is often the challenge Paleo group or is utilized by those who are using it for therapeutic purposes



They had these people do a three-day weighed diet record
Measure and record everything they were eating
They then did urine tests to measure nitrogen and the Goldberg cut point
If those urine tests didn't match the dietary records they were eliminated from the study

They eliminated anybody who had been on antibiotics, cholesterol medication, blood pressure-lowering medication, previously diagnosed with cardiovascular disease, anyone with any kind of GI disorder, or anyone who has had surgery on their GI tract
They were eliminating anyone who would predictively be an outlier


They then did a series of measurements (TMAO, blood work, stool analysis)
The two measurements that turned out to be different between the Paleo and pseudo-Paleo group was the amount of TMAO in their blood and what was happening in their gut microbiome

Sarah explained more about why TMAO was a focal point in th