One of the all-time most beloved and respected film actors reflects on his tumultuous childhood and becoming a dad at 21; why, in the years after 'Big' made him a star, he grew tired of playing "pussies," and how he managed a remarkable career reinvention capped by Oscars in back-to-back years; and what it was like making a period piece about obstacles faced by women in the workplace and journalists standing up to a hostile president at a time when those issues are front and center again.

But first: Bob Gazzale, the president and CEO of the American Film Institute, joins Scott to discuss the organization's 50-year history, its "all-time 100 greatest" lists and its recent AFI Awards ceremony honoring 2017's top 10 films and top 10 TV shows, as determined by AFI juries.