This audio program discusses the use of medications for three different types of alcohol dependence; a clinical trial of treatment for comorbid alcohol dependence and depression in which the combination of sertraline and naltrexone was compared with the individual drugs and placebo; a trial of risperidone for maintenance treatment of schizophrenia; recommendations for antipsychotic dosing based on international expert consensus; a 10-year prospective study that tracked remission and recovery from borderline personality disorder in a group of hospitalized patients; a review of the evidence for a dissociative subtype of posttraumatic stress disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.