This month, Executive Editor Michael Roy discusses nutrient-based treatments as adjuncts to antidepressants, the prevalence and characteristics of cannabis use disorder as defined in DSM-5, long-term mortality rates in women with severe postpartum psychiatric disorders, a program for children in foster care and their biological parents designed to prevent repetition of childhood maltreatment, whether the relationship between preschool poverty and school-age depression is mediated by functional brain connectivity, and the NIMH Research Domain Criteria project. Articles may be viewed online at ajp.psychiatryonline.org.