In today's VETgirl online veterinary continuing education podcast, we review the accuracy of a newer test (using immunochromatography) for detecting feline blood types (AB) in a study titled “Evaluation of an immunochromatographic test for feline AB system blood typing.” AB blood typing is commonly performed in hospitalized cats to ensure blood compatibility and to prevent hemolytic transfusion reactions or potentially life-threatening reactions (e.g., B cats receiving A blood). Blood typing is a necessity for all feline transfusions because cats are born with antibodies against red blood cells of the opposite blood type. For this reason, there is no universal donor in cats, and cats must always be blood typed and/or cross-matched prior to administration! AB blood typing is also important in feline breeding programs in order to prevent neonatal isoerythrolysis. Several methods that allow AB blood typing have been previously validated and include gel column testing, which is no longer commercially available, as well as tube or plate testing, which are both cumbersome and difficult to standardize in practice. Agglutination cards are probably the most commonly used test kits in veterinary practice and can reliably identify type A and B cats, but traditionally have shown weak reactions with type AB blood, resulting in mistyping of AB cats.