Ep. 257: Live Show Part 3: Not-So-Rapid Fire
 
In this episode, it's the third and final part of our LIVE show! We go rapid fire with the questions, but still long winded with the answers!
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The Paleo View (TPV), Episode 257: Live Show Part 3: Not-So-Rapid Fire
Intro (0:00)
Welcome to the live show, this is Part 3 of our show! Listen to Part 2 of the live show here and Part 1 of the live show here!
Question 1: Christine asks, how do you find out which vitamin and mineral defficiencies are associated with your autoimmune disease?
Sarah: Some studies have shown deficiencies, others have just shown improvements with supplementation, but not very many of these studies group autoimmune diseases and study deficiency differences across all of them
Right now, there are incomplete data showing which is most important
"Frequent flyers" are Vitamin A, Vitamin D, Zinc and Omega-3 Fats.
You can also look at what the immune system uses, Vitamin A and D and Zinc are key for regulatory actions
The immune system's proteins need methylation, so B6, B9, B12 are key for that as are Vitamin C and E as antioxidants
Iron, Copper, Magnesium (maybe more minerals)
All these have key role in the immune system, so it's unsurprising that these deficiencies are linked with diseases


Question 2: If my children (an older daughter and a baby son) never try gluten and dairy, how will I know if they have an intolerance or Celiac Disease?
Stacy: we decided to just assume that our kids have it, given our family history, and to not test
If it's important for you to test Celiac, you'll have to expose your kids
Sarah: chances are very good that your daughter (who was never exposed) will rebel and eat some gluten eventually, and it's ok to wait for that challenge
Stacy: reminder that some people can have issues with gluten and no physical symptoms. Stacy and Cole just get emotional and depressed when they're reacting
They can't tell you to fix anything if you DO get a positive result—you just have to avoid it anyway.
Sarah: research shows there's a lower risk of Celiac if gluten is introduced while breastfeeding, and the longer you breastfeed the lower the risk, so introducing to a baby is more backed by research
In the same situation, Sarah would probably include a little wheat a couple of times toward the end of breastfeeding (around 2 years) so they can communicate whether something is wrong
In peanut allergy studies, babies were fed a very small amount to help reduce allergies, so it doesn't have to be a huge serving

Question 3: Jessica's son did the cheek swab DNA test, with her second child she's just said "we have Celiac." Is the DNA test helpful?
Sarah: studies of people with Celiac susceptibility genes, HLADQ2 and HLADQ8, have shown that people without Celiac who also have digestive symptoms still have a zonulin response to gluten. They're still getting a leaky gut in response to gluten, even though it's not Celiac
60% of the population has one or both of these genes, which explains non-Celiac gluten sensitivity
Having one of those risk genes is a compelling argument not to mess with Gluten, because of the risk of a leaky gut reaction

Question 4: The Dr. from the Gluten Free Society's website claims there are two other genes associated with Gluten sensitivity, HLADQ1 and HLADQ3, which no standard Celiac test looks for. Any other research on this?
Sarah hasn't seen anything on that, but she's never specifically looked through the research for that
3% of Celiacs don't have HLADQ2 or HLADQ8, that 3% could have that other selection of genes
Already more than a dozen HLA variants linked with autoimmune diseases

Question 5: Can Sarah share her Paleo road trip snacks?
She didn't try to eat on the road, she packed picnic lunches
Grassfed organic all-beef hot dogs from Wal-Mart! On sale for $3.50/lb
Sarah had some canned salmon mix for herself
Her husband had leftove