Everand Logo

Welcome to Everand!

  • Discover millions of ebooks, audiobooks, and so much more with a free trial

    Only $11.99/month after trial. Cancel anytime.

    Stem Cells and Aging
    Stem Cells and Aging
    Stem Cells and Aging
    Ebook1,106 pages17 hours

    Stem Cells and Aging

    ()

    Read preview

    About this ebook

    Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process.

    With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging.

    • Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population
    • Addresses the effect of time and age on human stem cells
    • Includes chapters from contributors exploring the biology of stem cell aging around the globe
    LanguageEnglish
    PublisherAcademic Press
    Release dateMar 17, 2021
    ISBN9780128204139
    Stem Cells and Aging

    Related to Stem Cells and Aging

    Related ebooks

    Biology For You

    View More
    View More

    Related podcast episodes

    Related articles

    • Article

      THE renaissance OF CELL THERAPIES

      Jul 28, 2019

      DR MARKUS DEPFENHART, PLASTIC AND AESTHETIC SURGEN In the late 1990s and early 2000s, there was huge hype around stem cells and their apparently almost unlimited potential, but unfortunately the expectations didn’t materialise. However, new scientifi

      2 min read

    • Article

      The Contrarian Who Cures Cancers

      Jul 30, 2020

      When I first met the immunology researcher James P. Allison in 2014, he was just becoming an icon. Columbia University had brought him to their campus to present him with the Louisa Gross Horwitz Prize for the new type of cancer therapy he had develo

      13 min read

    • Article

      The Man Who Blamed Aging on His Intestines: The productive, bizarre career of Nobel laureate and early aging researcher Elie Metchnikoff.

      May 19, 2016

      One day in late December 1899, Elie Metchnikoff, one of the world’s most famous biologists, woke up to discover he had found the key to immortality. That, at least, was what the popular French daily Le Matin announced on its front page that morning.

      13 min read

    • Article

      ‘Failed Motors’ May Cause Rare Lung Disease

      Jan 29, 2018

      Researchers may have pinpointed the cause of a rare genetic lung disease. While most people recover from respiratory infections within a few weeks, for those with primary ciliary dyskinesia, the sniffling, coughing, and congestion never end. The tiny

      3 min read

    • Article

      Who Wants To Live Forever?

      Mar 18, 2021

      Who Wants To Live Forever?
      2 min read

    • Article

      The Potential Of A Human Cell

      Jan 31, 2024

      An increasing number of scientists have become disenchanted with traditional, animal-based methods and have turned instead to more direct ways of investigating human disease and developing drugs, such as using human cells in various forms. Cell lines

      2 min read

    • Article

      For Better Diagnosis, Watch Proteins Fold In Real-time

      Jun 10, 2018

      10A new method can examine protein assembly in real time, in living cells, to find problems in the process and diagnose the resulting diseases, according to new research. Proteins in the body need to be perfectly arranged, or folded, to do their jobs

      2 min read

    • Article

      A Little Bit of Stress Keeps Aging Cells Robust

      Nov 13, 2017

      A little stress can be good for cellular health, find molecular biologists. The work will help researchers better understand the molecular mechanisms that drive aging and risk for age-associated degenerative diseases. In a genetic study of the transp

      2 min read

    • Article

      The Cancer Custodians

      Jun 23, 2021

      Part of Dennis Plenker’s daily job is growing cancer. And a variety of different ones, too. Depending on the day and the project, different tumors may burgeon in the petri dishes stocked in the Cold Spring Harbor Laboratory where Plenker works as a r

      11 min read

    • Article

      Healthspan Is The New Longevity

      Nov 9, 2020

      Healthspan Is The New Longevity
      13 min read

    • Article

      Faulty Glial Cells Are At The Center Of Huntington’s Disease

      Dec 18, 2018

      Support cells in the brain are key contributors to Huntington’s disease, according to a new study. The research gives scientists a clearer picture of what is happening in the brains of people with the disease and lays out a potential path for treatme

      3 min read

    • Article

      Could ‘Reprogramming’ These Cells Fix Damaged Hearts?

      Feb 15, 2018

      Scientists hope to one day create new healthy heart muscle cells within a patient’s own ailing heart. A new study reveals key molecular details that should be useful in developing this ambitious approach. In the study, published in Cell Reports, rese

      2 min read

    • Article

      Opinion: Microglia: A New Target In The Brain For Depression, Alzheimer’s, And More?

      Jan 17, 2020

      When microglia go haywire, they destroy synapses and neural connections in the brain that affect mood and behavior. Calming them down could pay off for various disorders.

      5 min read

    • Article

      New Method Can Tell How Old Your Cells Really Are

      Jul 12, 2017

      A new system can consider a wide array of cellular and molecular factors in one comprehensive study to determine the functional age of cells. The system could eventually help clinicians evaluate and recommend ways to delay some health effects of agin

      3 min read

    • Article

      Get Active To Reduce Your Dementia Risk

      Jul 23, 2023

      No matter what your age is, start exercising, even a little—it is one of the best safeguards against dementia. People who have remained active throughout their adult life are the least likely to develop dementia in later years, but even those who tak

      10 min read

    Related categories

    Reviews for Stem Cells and Aging

    0 ratings

    0 ratings0 reviews

    What did you think?

    Tap to rate

    Review must be at least 10 words

      Book preview

      Stem Cells and Aging - Surajit Pathak

      6t\`book_preview_excerpt.htmlKsɲ&WrCـͲK4nTѴd|Vgrz7c֋^8sL{78DȌ?wmr/ѯTuY_/fY2D(SL1.fYdfi>y//_j&͛l7jWsݕ_444:im;0Ib?jy&zU [fŪ.f6uWɓld"+f轙 K4eyQѿ-^L2y:h&ORCiR O/sLFd<f<^EJb)-Lynr33exK۔لaz]J3hR$h*f zA͌IP1M,kbba7ө-i)hy]qWKPS3z gQh:"SA^E FME,%)]efb7fNqni HIRg6>iIZYS ǥ-$Qqj}cq_S*[(1X6ىĕ]ṼiLFmU<#//EFj #^DigI~L˺1hohZhB[ni1e6[a͓ؑ& v`4/鷶, ,y'iY2cu+~=+pxy%[.xD "NnXJ+نз(o58Uw}t//?VFWUx>ӽP9cf`XҼn49xtE<7/4iU6͝xsGn5pbIɉfi(:Ŋ?\й'ASSD#Olp?4:2#t!NI|MOi3F6 G;mᵧЪzfib]G@NHk=n, A  z=O#KR8: /X6-sQ->K|œId#^mT0\ۂI FR7ypx^L)iAnz*I%TC )^jB@UeczNp&q,3`fT % ctaтl}oTi'YQ$V .6KNtA E 4FÓ (ǵ\/rĤ2e /7:ON gy6l4hwxd]Wl8y=az[rbJ.̝4gHWI"[Ww/;eF$18 A6wt@,r≶ا'0".m,L;+&!Pє8 9E$HC $}d\Dc`G&w\!B%UZrG:⠡o5SSE_;(056$u-{ xŤj?30ML.fƷEetRM!km xL-i@'(,Lı^D@ y#9. v6s%lG#2v=7B_ Jx'K G4ǔ$Dۥbz׭2.=Kn0NLd͙%.E&G QJsEӴDXV1L؍ȑDs<_u[Ʃ{ L@^)zq$ ;xSID!Ҽ۔!8bD4eCL Р jV=7 y$y4^{e Ex?v[Eا `~rY;IX*LpL%іyuDO?Ĵ[-z,$USNcA:۱;dz2K(ٺ|q8Dǻr/D$_1~P6E$ݾߟ?ۊ *GO9)JH"fE)ǂM)J$L$t:G$D d{" )ig9Dk_{C!J[hU}-FNaҀ@$n <eyoSn!,Sٜ?vljceIZZg0-V(:MƠ ^?;g<̽>O,6(%th^n?Gd&1l(Ǔ<30¿V5-,pd4;&(u@Hz(C$g 6!X'#}bB?qKWIWk\tnc,3!FA'K-݄.ȍD@)9p.SJ;ĥ {0U1ӓ0 dc%Jg $YZe]Hl+t 2@ AdSa.>%%L/B?R*$X!NjSY?@5ijvL,'ꬋd?#At*I .!;iUP-WJ哶^H-R6LƑB8fAo![׍vEx:ygZKeiMTC<$Vc-nyg dUn[!835f-K܀Ӣh&UId/6=j{2)&۰$x茥kXh/2">''.aK@4:^`YԚnhvC݇6šXy.j%*}=J)Ob)J+<J=~xBz %p=C\ Z|4;f`r)=3#\]Ir;d),GKmСq i͝c{%]PYMf{yAܹ}w{oqMV.pcٰcysĀs'v `-V0788v zqAXxjyX\ˢlC;8lsA8 lc22,I : @4RVmi  N, v2՜mCJ[s{ m&LڥV͌,p }"t?Ĺ.["mb%̸&LZx.'z$YOCJ Cm0≮|!.꜈ qcKYlPϒV͜ gɥ#j,eJK(W^a $M4$66s*s<[Q,&b_OؤEb2qDzp0 c,/nD:MN%%B-v?{Tl*BnFsd֊s|ShJ?+aaC낇r>g=r GtkRIԃFT]ڔIfEn0\ݢ_ghU Ym)m"$>AO'Hi`˼&r*y.V^И"Ͱ]vc&"R V]$tswzw[M X_8ma] -E0A y2W8OyImCM~ϫ ~Z@UU!dܞ \,>$mIC]*N>T[)9k;Daж+jz;zvͳ]\4$LjTƑ7ò^-tȾJj] y *QpSE任hҴ[E8HGiu֡y_2.ˏ6.K|,|=p{yϔ{`JqVAjmѺ5} T8Tk0َc)&$kF&<^˟⑄~yqH?L@۸bri ʿUXN R86U>V5K[e2c>vU?0tǷGGmʜSLn[Z]S.f:vHh>^@;TXgK h`;Ap[ 5BԶfײj!i <`D#Ohы֙aFa89R=2ɺ+":=ԗLgCիmmϐu]Z-xr\QFVUMv73AЕBOKH%'I̒?@ bK6<q ExH:'1 cvaGf{wA1~R\ & ZaHWj'P0PYnq\4*<Z*f*Ȑf并67scE[ &شe(t @ ?D~&i;ӟ`&ODG;ˇ_iկh S:D⺶Rf!TSLQ[UgiI< ˜tF:*vTFS#;"4f(ۍDOg&w*U•#7ݶJ7:1K })wʩ~%ꐭG|Z%)jDl^@-i#,;]Y 䘬G6UVPX*Љ2gIǭkN 5Y娀NS2sPǙTS2n> BE$;pk{"A mj6<#9NrԥS*[ǎmoز(?qUppϽV4 \7Y.o {GDhWl{ q{ & $Dzv(E!7x}Ji,#'T>u}1BC66敧@sgM^W%,YHPy?= ͎6bC$V3Xoi|VTV_VvGh<襉zox&분qj[7]p\sh@(ZJ;ص?R۔zXpFOh4Y p]IZH)R}Ufu'Sԝ#O#S-51a 6Srnâ99vZꄫC{*4b wcҌ9Y6czXpUeےٚ *K+n%Nȃ4C/T ub^V\ yD_#c=OS;, X/fփ))AI}_\dN%ђUI QM_-gs% .} idN#?L8Ѷn3@{HܮT2h[lN0W=2u P5Ir7Hpv5̰s߹rՀް(pP9r>>Z%d$AYz;9G̑,9]2 zSy- \-fRJg봼̤Pu*['>Y5k'Y4Ւ. rv]~=Ԩ/^%+L|sAZF5}JyUZKM Z59JLmR`Kh(*Oälfmz+o̢H|cC]o,Q!cY´wٺӝfkNZ>]XJ IǎxuPt*˰s-S'hF_{z`2_Jr7ކ".iኲ5%dZ|mݝ|:z!zY \@AAXuhW;_ߍv>Y/Ѫl؀6Xw TOlJ ]Xo2rPm,0 F $p [G#0~7:ěeSG>=/4 t M(~^ Kϒр9u4n`ʨ~&S Zn3 zP Α$\J1uyAEhBXL3ٕmVwڵ$7⽷4Aۮ@]7Z8ؐ(s ;txy_SNtC&er?uI3" /`k97.ܱɹ|T(iXn.ӂwv?;L,N5iwGk"TRі`w~xMg,ٷtZXSe\w<$*5a6eexPU1rsv0Bfwtz4>쎎fw< Ҹ+NX:yipy0 M H?]9)+)43-KAmt]}+tyx|xpw2: $s0qM#K\{JځM*2z1v+ ;KZd0&`аt͌6MQņƖBFKhw`.Ew<ބI&[ ق63q|*aɃ9OGG{'=zw5pL[b{[lYFډ.Mv7KNXƩ:<' wױ3CeZQٿ%/*@_B֐F6_8Cu@b4'}o5g}(Dgt(fļZXLB９3}-?%2a|׏$]O ^xutcQoN h)NBit%x>הp:ߡ *P >KDT&S)┠zw]XW xKxnI}$g!(i" =d{8k^a+S2n/[|;om_q1r(q bU&ArE";<Ɓ" )d\|Y ~25IEe$ n$L,Y/>SCNxt!lpbr1v[?f,O6#bi 8Wa؟LŸrN 9{˵)A:{RFo y409"ҫCyf/㓊h|x2a:(3"q8gB;C^4}[}&xaH%P@VLSxqP}WVrKZDqՙQ{qz-Uk9݃uX0 6yeb hSprkxүYk\}ng2w'l,_iUpt[-6JZ&ŬpoOO4sqJoxzLvyG]E{?"rN>CGV#$,SHA`r~9؞[~&]46c"m*Jb#R,mmT QpliO.$Y8'#(U#MI .t/E.`4*^@d茾G'=7Da @/i ?΋@W aU FUe4UVP K0Bk )ce lH#8N'qd*”MST@}aPN,S:x8u. p8έPqSy.w9lԥ.t3s=A`Vtd5}ҒN2 Ol~%[P > 62䏄xFIǼY{]a$$A$ư<7igGmPᏌU!={3&s΀ :I] ٙN`gywz7=7pLjp|rGP+ ;r3l&g9v( n 3)iI.w\eM;>;&\/f=„j%W >rdD$)2؎:y:S?Kvk='eXÓ1:"2S|G*0Ա.4 +As|$ޝ J+{E[=,G|̱]du q֖pT \eOU\ZD,iʎ~/uĘī)K`&fE]c%,1~!]DdS,N (BwZd7dr~oc27 G[2p8H1[~ Xnf pu\Y6A_te La>=V?`'`ү&dtf3cS@S ̡~` dh ? NI}ˑ)t%p$ HCG F'ǘ2Hcڊ9W$E,vb2~DVMU Ь癩ₙp2ҩU~$'r89볶67`7Ɨ5nj&}G{' JƆѺ.V$1tEXOB2ʻu 19ƻ#!F,OĹ"iX̤ m Wl5 z-p)O}#y# >e>gzV}GQI͹~kbݶ˪'WK)-+>;9:`0pd4?Tp iV.>zixUJ|'fH N$Zr*SfҬx7C),sOVOQ9ov@'&]\Hf_(Z.08aaZI4!-ٜeG=<##yǭ)9҅Z;74.2Lf[?ig6ZRmj4Ws%ᮭcWFC8cIED/Kb|\3;py- e s53mNQT+h, gYH}X5^A sfGsn l/KwF/Smzp:<awv^$ Bf}8y:?I6r4n:u wDɍ4n9VѹE7`v"'#x=~768]a'hU&p-oخBpL JI*VHZ "E o"X^\y/^u$G?ppPOi>TYS%.kt;~Ƃ$7H Y?Sq\]z(.V4)pY(ֵyL ;ޱ $ "@+"a!@^ u|MP= ACKu5Elx|wzx<:u&وs|>اjn^rGG"/?4O+ׯFξݲrz)h 2[xnЃI4M ;4Ӄ1}NV;(C{60o- ~’&4뫷`}۶ _{H)S%۰c6@ pQGwr߃ޤu:e0ُsx_Û!*}wdbj\I{_6M>O'iXh6t]Ti:)qk"9xqm@uUa[ܞσщ$Эcl;? g8 |K؟ k_7^B$Mt 4rQɲf]P5,|]pr Վ$<ɊU(?$KV/f?іg-99 ͠~!{g᷒%tKpV\"p91ֈo TFF.-#cˢݣad3aU-k-\鱣6mQ  ^F(c4y!Aʀ"na=1??kQz-@Ԋ4Im4(\Z"\M5+jϕ2JBltwOÓCa֧I`Δ37ri=-a?'9®TPWPCV_: ]]׆$|!҃vi$RHF`[Þh?x#k<72U+?3D`O'Ao#E =针BZ0.{,f>`p~6zf꛴RXI2<맵i>-Jnj)4`'Kz}c GkxX.ԛJ=h{[GKn,5w#t1IG]H-W4:wbتlYl)<1ۂ6B|d f09?IDR^l f=:*@4PYa$o ụ̌rH`nk& IUmͯ"X;7@ΠBpsWorY h-Cd%ru B¨[U߸:wi3Բe]0m%A +w]{=NQ"lo@/;Q?uI'UFM.^"b$"kiw.M+VkZ2~snDn5`BG=(X] ѻFԖsGV$ BEwQ_\opunZ;۸ۗГx贈F4ma׬qi]OP%޹ݫQ|k׫cd6wDJLB+s5{}DFA>7>~Y)R۪g27 /umqns1;56nVDGSܹC̒'H3W&U3.Ex]M5oYhNׂoq9;i]-.uջub5t գQ$Eڒ/i9`ȂhWeѳᕰ6Eۚ!M>w&| fȽxryKZr1[gɪ3.n*Mݹ-YM²bqkG"'qZY\ܼ]Շ WO DZ(0f|5L-E;eqpVR,tgfe)畻ظ? 4]()AivۏHz#xgo7/7\',01PڎB95VXVqu,t`_7CzG4ŖlY2m04LO,|kYnLld|}zw ~ tygLj܎iH;, !*ytC5Zm ( - 5?WbY;tB4绲Ą-19KK[qm-XD }^d;Q^BSm WvW?_7Ҋj-nez|$sd> }OR 7ljosbeQĶs{->PZ E&1,ٿ*3_V=dx݋Ü60?6f҈] jϣ}^7V_\f> EECՔe\ %4&/f:PJkג_hv–ׇS(ntu8iYW!u.cpempPuW+|Jc@@pz:˧`-:.eZ=ޝ|#Y7d$6M2IrD!+p|Q$OVfY?p8v?RLlŗ2Ӑ agJn0;׆nvX`"!- t7&pPyڍ]dKc4B 毮uCz&t"C݉p]RwTw~9!ELWF0W9)NČW:.H(}rg|{m`{!^U |2 mɥ 4Ad˶^L`zt Z"ju)NkV&vM/Ivj'Π9."l?0v\ld:BBzx7x\`9) QZ2 lsdw 6 C:rM\nnI֓3|hh|Z/oJmf~-"^KyGP S5Kmaױhj1w9>op^E>AiR<28ہ;8;s$UO[7`YTGmnz"so~QŌ !(PDp5ZDϤ})PiP4at=5zS"yV@R ڼpV20{k%LfgO. wΕn"/A<3EZTܸ#.x0e""|TY M6 .< "rWØ6k ģx?VOؑ6GTE@:"Lfu1]*ڡ2hk+2Q٤${Eؾ{2"o]]߽p,BK,޸h_rFa& t>wA){߰SjNA;7Ee6ћK9E$y )"KHcu ?汷k WF\Ć|B~Jik7r~6D*T=0pN,!Pl*ݜ^*DWeH47X/Q>65hǃJЪ;ƹe7wW חg[]%@K̤*t9A縺g?s(slRaF:J7sN#nwwWgÁwf]/p(boTs3 x| LdxPc3n|ɝ.\oJ-/*//ճ{r\Afboeϳ Pp|;a C08L_q sWi?hIr6k-Y66^t*SzؔƔJrEma"V}րa p!8"ꭰ 1wn"Ქzi,[YIJ,;xm _0t>^֍g4X.HܺBA^]ozE8^!7./bdJ()ImG8fɅ3aջWJ
      Enjoying the preview?
      Page 1 of 1