Everand Logo

Welcome to Everand!

  • Discover millions of ebooks, audiobooks, and so much more with a free trial

    Only $11.99/month after trial. Cancel anytime.

    Autophagy, Infection, and the Immune Response
    Autophagy, Infection, and the Immune Response
    Autophagy, Infection, and the Immune Response
    Ebook823 pages8 hours

    Autophagy, Infection, and the Immune Response

    By William T. Jackson and Michele Swanson

    ()

    Read preview

    About this ebook

    The relationship between infection and immunity and autophagy, a pathway of cellular homeostasis and stress response, has been a rapidly growing field of study over the last decade. While some cellular processes are pro- or anti-infection, autophagy has been proven to be both: a part of the innate immune response against some microbes, and a cellular pathway subverted by some pathogens to promote their own replication.

    Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection. Introductory chapters ground the reader by delineating the autophagic pathway from a cellular perspective, and by listing assays available for measuring autophagy. Subsequent chapters address virus interactions with autophagy machinery, the various roles of autophagy parasitic infection, and interactions of bacteria with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, including antigen presentation, ER stress, and production of IFN-gamma.

    Designed as a resource for those interested in initiating studies on the relationship between autophagy and infection or immunity, Autophagy, Infection, and the Immune Response combines practical state-of the art technique descriptions with an overview of the wide variety of known interactions between pathogens and the autophagic pathway.

    LanguageEnglish
    PublisherWiley
    Release dateDec 3, 2014
    ISBN9781118677735
    Autophagy, Infection, and the Immune Response

    Related to Autophagy, Infection, and the Immune Response

    Related ebooks

    Biology For You

    View More
    View More

    Related podcast episodes

    Related articles

    • Article

      Mechanisms Of Action

      Jan 22, 2023

      Mechanisms Of Action
      2 min read

    • Article

      Message In A Bottle

      Sep 1, 2021

      Message In A Bottle
      8 min read

    • Article

      This Protein Keeps The Flu From Making More Of Itself

      Feb 16, 2018

      A protein called RIPK3 could soon help minimize the impact of the influenza season and become a critical player in the fight against lung infections, according to new research. Each year, influenza kills half a million people globally with the elderl

      2 min read

    • Article

      Supplement Superstar

      Sep 27, 2020

      All we’re looking for at the moment is the easy way out—the magic bullet that is going to deliver us from this blasted virus. And the media and most governments around the world maintain that the only solution to COVID-19 is a vaccine. “We’re going t

      3 min read

    • Article

      A Vaccine For Plants

      Sep 1, 2021

      Just as humans can catch a cold, plants can also get viral infections. It generally starts with an insect bite. The virus only needs to reach a single cell to hijack its machinery and begin replication. Progeny viruses are released to neighbouring ce

      1 min read

    • Article

      Gut Bacteria May Affect Respiratory Infection Severity

      Feb 2, 2024

      The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, according to new research. The findings in the journal Cell Host & Microbe show that segmented fi

      2 min read

    • Article

      Accident Leads To Basis For New Antibiotics To Kill Resistant Bacteria

      Feb 22, 2024

      Researchers have developed molecules for a new class of antibiotics that can overcome drug resistant bacteria. About a decade ago, researchers in University of California, Santa Barbara chemistry professor Guillermo Bazan’s lab began to observe a rec

      5 min read

    • Article

      The Science – And Mutations – Behind The Emerging Coronavirus Variants

      Jan 15, 2021

      Genetic mutation is an evolutionary fact of life. From humans to insects, and from bacteria to viruses, these coding corruptions can pop up anywhere and bring about a series of changes to an organism. Cancer is one of the more better known outcomes o

      5 min read

    • Article

      Genomic Loopholes and Other Weapons: Turning bacteria against each other can help fight antibiotic resistance.

      Oct 3, 2013

      Back in 2000, before MRSA—Methicillin-resistant Staphylococcus aureus—had become a household word, Nobel Laureate Joshua Lederberg wrote in the journal Science that “the future of humanity and microbes [would] likely unfold as episodes of a suspense

      7 min read

    • Article

      Why New Antibiotics Are So Hard to Find

      May 24, 2018

      An 86-year-old patient arrives with a grisly foot injury.1 It’s badly infected—not a surprise, given his chronic untreated Type 2 diabetes. What is surprising is that meropenem, a broad spectrum antibiotic, and vancomycin, known as the antibiotic of

      8 min read

    • Article

      Welcome to the Biological Age

      May 1, 2022

      Welcome to the Biological Age
      9 min read

    • Article

      COVID-19 Vaccine Makers Are Looking Beyond the Spike Protein

      May 21, 2021

      In the race to build the world’s first round of coronavirus vaccines, the spike protein—the thorny knobs that adorn each of the pathogen’s particles—was our MVP. Spike is a key ingredient in virtually every one of our current pandemic-fighting shots;

      6 min read

    • Article

      Here’s Another Reason To Stop Taking Antibiotics

      Mar 29, 2018

      Mice are more susceptible to severe West Nile disease if they’ve recently taken antibiotics that change the makeup of their gut bacterial community, new research indicates. Doctors recommend against taking antibiotics for viral infections because ant

      3 min read

    • Article

      Vitamin A Helps Microbiome Regulate Immune System

      Dec 19, 2018

      New research uncovers another useful role of the microbiome: in mice, the gut microbiome regulates the host’s immune system so that it doesn’t attack these helpful bacteria. The trick to the microbiome’s work with the immune system is vitamin A, say

      3 min read

    Related categories

    Reviews for Autophagy, Infection, and the Immune Response

    0 ratings

    0 ratings0 reviews

    What did you think?

    Tap to rate

    Review must be at least 10 words

      Book preview

      Autophagy, Infection, and the Immune Response - William T. Jackson

      ]"Hdbook_preview_excerpt.html}r#əiXHdnJ%I&HVJ7b!y;tF9XVo'-"jZK"_7 {dH'ue2 o^GSWzQ,gi**Ϋ<$U7gU:-$UYr7Mu>Ճ~E^ɭ.*,SHe)~n \kfɡZ.zrnTTS(&ҳtQeZm *3ja\&G8] 3SU-Pg_Ma*mVd¨Lz ] Vh " 1͛$>RDXƝkL:UrG:Sp3~ Y?l?jw)FfۻJ:fr_<更|Q,|>HXE󡧅-ᝫ$btp8}LĄ6Â_J]69;Xq0OaifٶH/t"s2e&')lUn^˟R@g9J?/ h_4I ',A`/ J= $'+`U yh0*\g؏  uϵŽzu 4.$t=dZ ?G?;X3/Y8֤YlTNp |͠` 7 hyVN ?3:29Z٬xJ Iff@qL59:=o WU'S`+?Hu oMGtbFLF/]5 {ߍoC:] 'xqgTsViz@RZ Ԧj ·tޏ8SūP]x Qu\MdfauqyN>U ð5Jw0^y` GU3@'[cz~9HH/KJ<-Kֹ8Tnu"ཪC$^=IcT 2vRWs+\ B!lX18K.1%&_`ތXwx䏝94pi6XG\|Peic9KIsS_N?ݣ+ z7`~}YCpeinn"rb' xtga\d r*s9.x…|QgfS]pn#d^p98AN;VY .6RF|k}gJ/P@õt3DB25R?>D1}.*z3+b}\?_iXOow ^]oWOiG *OPDmB0?(]/SZ}Eo,HX`iΈVSErZY*)6-bs-)_4Onլ#w >&.`3thՠ f%Q"٧;3E5G = Nu.!SR8SNKLuhq [n!x:*X<5*6hgQM0`9[$OOfA oU}o$ T9z`V~ ?zq*[cu$[S䳠1Dţ =1{YkAR=lQ%2]rf1ts&XJ8u:]כduIP(K_%Q:?bJUB?%:0T!S<u KESǜ`n&[v4jLln9{J>R#ܧy򇅩F/ n B% p,-^Ir,=${~17 U%kIdb1-j)@8eP)$h ܔ4YaFN(P(B="sWlgNwL+'pQfjVk `N_5c 8KR|k^[Uʣx؍P=pW}UHO={T!5B~ k~4Y'i +$+|hR~Zm;F(L@ +`0< R+7X\OaS[@}f_7/dEld1hS|;>'ϊɅ9-6Q?Z%>2R^"!bd,#$8|hJyS6n'Eg,0yTSM9y<L3<-vZ 8 .K ;vz_* i2h8˜paf5׏c\9&Ex9@sԃj%LRagBRO# =Lҩ0x,R)Ygj  녀g⏿M b$o3S,V 6UR,\mJ6=FT<b NU'+Vpz%)xKa^xA^@'b` 3gkvr5@zVBAeY(kY20Jz ,U,B^A7C;!$ Kx ЯlH8H ㎧j,}r~V Jj̹ylJm֚(c&s&Q/Og@1l8,7+__y!$<7+W`L͓H/$˯Dy{7}NHX|PԪc$2.ɎGx vwLPA؇ VQP`<_揊c=ϊM)@"tCb},/hV3hZLjo_˒pJ ʐ,&$s|- L 1|J<ݏ~a>JOSB^dA9N<~hUKC"~NJ' %xA MXD+ '[0To'U`6O3(X^! JmU%} Vr^+&I!l1(Ҡw n))I{ \O0ؐHIbcl||Q|MsZ5*"\*Av,cd#X[v]' =6Gp`,P'WgGIo~Ba ~`CV4_*E8 `@>MMSNl3FRVfH>] p25} 26vSƬhUa x x_M =jk /T].%Z UD?55%8:2j`FS#6ba.Y *gRl CR~zAޒ]_i}#A>`(2HйCY^e<xl93Omg2A 8#D'WаBafBdȅG0B,fM>'$S|宄 ;RkCإR1pbvk׊wf'X ǕR @$5@҇I=# B);5ElcV)X~Qfxf(%`$ ǍO}:`޹wymބ{Zٍ޾} vzU]Y/7qQ֫ߧ"!+O,DP-Bm /}\paelH  zOu^QkBŢ\Q^И%UgS,B啊Iψ"iFgKw.(sņ rҹ)jfD_2J`MhkFl2-`a0IްBc` NT㾄q0.ϑܬ7A5ꠟ`%錨CVFYÈ,X\2De~r> /=Rs[o6S/TKT1+eH0i1X<$A#>26>@UŽ ƂDEO aW8t-`gگoqGp{wYfzS>'!IhYcZX9݃[/ Ch s?<ӥdj@2f1& ˋ~Šs|CJYx`n 4fCbhŧ Z Ũ0M<<98S4 9=|}'(n,.b&E}y|ux;%v CU,1Nçi,b}p.i\ǻ{{^`TrpGwE]^6+J%lǩiuQo"} nyޯ|TUֹ7 *׮^G^*a 1)ٳwRjJb"uyKEO3"ceh71OLo[Cxt;~$ù@UfNR81'C`Ia5Qrz{ 5 )%NM :Kz}C.+#r<(,\ V)(N;^"w[Rơv:_HˮtIL [8Ia9-W6D8}L9L>'Lv8m~^Zzr.fk !K' .B,%=*{)Aҡ&ߡ?uS 0gA=װQ>ˋHԺ3ۂ$' Hu,:wɭSS >tuj5~Prw0"PEUN4zQDj+KrN¸BWBx~$[\zﴎqFݤfߥ@kу T?"|wrӱ&iPX>Hɤld^JDjoXX$D(S=D[ d:~JIz$dq,A#%Х5 v$3J3 ˃NH`HW (J*7+3޸ /^R&s ɩ ηx,f\"鵫ڵ{uCd#I/r=P,:(ɓ}2[(2?pFHrjd2,f7Ćw Y%Wg,Yo9,J,oe*//Yvό`^HJZ (TIZ3v|v ~CqfXau:ϔ ̈N9b"+lsw]9p0wAD)AyO-Cgppxʘn R)R"%5igCOvV#xS.Ax>9  M6"ءᩏk?JJ)5gk8ahn[S.}yt+Z~HGtlHomTnG[z_;T~:)[4UaN;mDz1*6i 7qYH|dzɼ{ZՃy9gd|oRl`#%VRĠ4B>甆G d, mGdۥH!`RI3 S:x;#XWX3,hpR+*STW"EўKq-&qJ`ag̹YZTy nap9L_9* 7SA1/}U6 N͹K}"o# .nw@$u)mDTe2qoVͰ zh.pƇ wY1hN R )8 u3$PlM QǠ%H3n! 2.fP,ņjM]nOrIC >X>׏܀q|谥MBsӞ`ޝuXg^Fռёٚp)N{ީ.8.2V:H-Tz0Mj;9᜻QwJMZXX85cXf"EA ͕!(hKDbRJGjvtr%̒M]!Scb/W&P[zLDm"UQj'GA52;9:KB_R)™JߏDzw ՊI b+9kP,AqkC"ʼ!)F עd͗l'J"L[a1K4sԹ~̹#}6iabНhhZYt ef\w}_G+ލ!+]nÝw4UH!nlUNBdHƑ4 Ӆ2p, m[1?Y E V#*M|0{o؏YҎ#ȡģWXiն :9UP6\ӳheݤGaOu޷Hvy')HPckNm[YsXF.vdr۞B$epCIMX80MS`ajL>\!82Pԕo]hxT2Ʌ3TZ26>neM"^h8nf'F4tVjhEX3/Vo୷SjOr4"9ٗ[UV8@C=Brǔ6I'kC$o͵H'z|} ]4wJGJP'0(}W@D,#;43疉 !9~WͣoH8V} j3μNxQ`ڨ[L28V8}ai~,U ʇuV7 @v5=Hb%Vlр||#,5<|.d=xˤY{\?ƘM x|4_pT=|YHCvSuU|>́ƓBjkn햾Ć޵!'-Ua~ǂD+BϪ*1vRNe/^#]/dxxO ZHqvrO\n  ޥI퉽|cߦB}"z$E~KA?IjrB)Zc|1gyڻ)XZ# 3]T'(q聒96*pTzYMRa"opz!:)r8y֙cɁ 5Z|=@c4b$AJ~ y˟9u34<`@G6pL?l+u6:$K/OktWK SvB!܍{(@6C^Eҏ%ׇtpwxDy ǽ7/SD3G%8:5EH_`w~Rv\9Chf0Yx*q"5Ö)TcN67 tcM3.E ]^iw. s[ sdܷcY}΍V[mWgQGE @tceZ2@ 9L $,Ԫ!`'0!Ĩ&Z *m֍pml,&$ 6D8~T^R@*P%O18D|_CIOE&aMgRN΄#Ia'kIOߩ Wҗ>6BX.. ފ7$e1wA%H!UjTQBL.P0j]"AvtA֭ZU9DEcrd9e\ą*wPEBf'5W#Ѭ 60;x+^_&8`(FQ7QEHaG7Yc#'] Ήhxb!U٠*A2n/+i8[~IwN x4jxvٴ>jڽ{uqbz7{eWq- |1Bv.!9],6)w]誩'}/Qm\}ls yGPHVbuqR\BdVa4IkgkƇp7Ih|wý%\PɕG%CaP|jf.j_K4JiA,";HʊCOԔ?M '57mO[7&ԛ"Sꄹd{k"SW#DMJUUD) t˥kQts:sl-Gs1X~$/ vZ PijʑɆ'LWw1緫2Nu6wM qUm\ҽ)E/:~HO@>4ސ_tze )o-)wRs7e\7CA/N܆ڿ1;jy:NoֿCv@Mhx>F)S_ AG:A ;~[uȬ0At d,&"L=ۊo`1P=;R"CYKW31fɮܰOC|$Ri&lW-yDyNF%SaYWvzu|7˔J\mV: \`?YJJX㋁nLղ iD\%̣(aJx|;=Zsq w%c= a g;/S`ݍ} -s)q!Π[1 J-2ai: mIOI2o! |SmެF%^ sBco !Tڎ(Qy)V5m86аG'x&,/QTlB)65ʰhr+#]ҕ"m$-h30$pn}8* j Qv5Agwkf= !YՇn]ws{ Kw}kaTh>琰 QkMCO W7%E3wPVS۫jASK0}}4Ǣz'M9`\vYďf[VXTZJ`$ާOe1ܳզY3G5]0 +b]mȚ QXX#IF{tm0Ub%Ǝ`Ķ qEg׺Kw|}SJq8l Q2Zn&S΍Oٔz`]`#(ĥ zlxmsHVFs`URR#6: 9ׯsJi5+i6d[32_'ib1O[rgmm˥L7L"asEp w o EtD1,6Zgg_ůsO'Yگ픾~>ƞ"*WZ MϽ?*㢳ȘEETv{ 8:}-]If:^4g\"C)>v1DQā'b.r_0#HJ-wĐj*6uAv'IvY$+]k.fVpau-Te ɏeg BKeHP0[BWߺdҜ.  z"uJ2•84q;&{^E,H$ ;z1RDp8MZzrIf{_b fpiiAD#gl0ֻoB jmzœ^ +#B+QۭxK?exKAcz+:mH)xIb[dpD?.&mcM9;K ~FIrIJS;_"Ql/Vx)E HXx=g{D|ΠO)ѲQ/Ƕ&񐇴#kW&XFDIƲ9 ySx0=5'56=ˈHA0lA!xG",N^0 }9;cg9fP+^V64i ImyykWԟ-*ѱ]Ѥ60n XXth?6CE|;ֻJ#ԓ5hY=||#P4qĞ%7y/dَBQ)CMz[t Q|%mӆڡar69s2==o{uZv:XDGZ]!U=GgkǶkO W{IOMJ]r+ ()_b7Eڕ.7a9Pj}B O<ۗdLq^57|r3{DpQfW;x4:4U' ^,HAXƤH`6)zdZcP\ilj5 8M" POQrOEWxv("ub8vQv GvhrtZ hdح1Bnq.;lRykۼS]UX=>`os585) *Yk`zfX38 3HNg꧟0t? @K|!T!4Lz<d.E?b^*]soSKK݈5#:KGA2}sL#gXODcrj)i^ Qhǀ y-+$liC$T<EQ)h \hg0(ae)=s4(6 ( ._{*gd#C|B3/OH ^4c?fIo`4xx"t=,M0Pt%~i񲟬_ Y I/}OD |"/2<;c ?!` ףFvrWO#g$x`-Pe~%fI9؊gP՜b9eiRɪRP@kQI!L( ]xU[Ap԰9HT&o.9f/QezQH E2^!en*])ux"E5}<ݧhs5Ej "^ z>}P~%*VJngϓr)Zfn+TRat6cE@Ĭ *gr74t뀰E,cov{+;"7vbB>zRCIyڼցzayP-?j?# btgVe35gNy>N]");=OckRG"jņvCV|Iq~Fx 4t»\934WEz,kXS,a5 ne%y{oe`^㏨O PxbSt,3 2ՙ&J Mgه;qT 8V5Mcn8^rCɶJz̔:̌5$<۷@ݗRRʶ*>Pdp7:BBiPz ]y@^g@Bv!JY"0@Rt3rPi5oA h 7^x?֢K6fLBEg!Gφ$S<5ɨ'. A3]rs^=Wcr/wpWtO lMW%t&=vRө*(=a4C;aٹD&ےf"~DF/pʳA+;w$tNHe+J at ZBȾ 3><|2ho I}f>#9H=L=^ ]oi7}J

      q֗01IЬ6Zuw91\8N`29JhcREC< }SF#NIRJ/P. ^m2C,6&:3]DK=7nkEG.+- A#6&/^zAFf.\ĔL2frqiDj h1O^ Sc 6* *^:obi5r`= tɐgHEɛvcɷ j/PDg ;W of*]OĞk5r{Y/k(o @8AW{5 T;y Gr=QXby!G3l3x 29SSUO[ P| &#S*cr~:~cF_Ej[Zf_CPpfK13\1jX~T+-Xv-Ow^,uá}l | {:o" wR1s&!Q ~Zl h>` h*9.}u#R-ر\gu&BoT껚 =nV2$e&A@?Knc4:ƺɶ,f5\la[@giy~x2qr*v}V$˺#4d7ou'RK✓CVep9n9^wXndG&YDfG'Qr?|~ W証yCN~ѦW()It=䠭HjAx>"OЛ' PEw=, QFU2M _ӝK] ?ʖ^4t|8pl|2zHn(׮2.4d`Yz`"O.E@ތ㎗8Cn/ qah|T$-pv@~T$(^1z;0jh'+M\.^E~"eFR]5p5'$ W+9FeqcΕs0TЀX샒Lcء[@zUOvѕu*Ȓv/)k_x; [xx`P(Sc|T\&Z#%%xtx@ǔr\{rhQ>8oJ7W-/&(jUH%Ok-6?A/\礳lX<ۅ I#=nՈ`+@g"Nӂbr rV#aZ{T/ F;%AM*#te (]=52QvYSl Ɣ [vUQ ?P

      Enjoying the preview?
      Page 1 of 1