Omicron Won’t Ruin Your Booster

If it doesn’t happen with this variant, it’ll happen with the next one, or maybe the next. Some version of this coronavirus is bound to flummox our vaccines. In the past two years, SARS-CoV-2 has hopscotched across the globe, rejiggering its genome to better coexist with us. The latest coronavirus contender, Omicron, has more than 50 mutations, making it the most heavily altered coronavirus variant of concern that researchers have identified to date. Even in the fully vaccinated, at least a few antibodies will likely be stumped, and at least a few cells infected. Our collective defenses may soon bear an Omicron-shaped dent.

But immunity isn’t a binary switch that some party-crashing variant can flip off. Even if a wily virus erodes some of the safeguards that our original-flavor vaccines have raised, it’s nearly impossible for a variant to wipe them away completely. “I don’t think we’re ever going to go back to square one, : first against infection, then transmission and mild symptoms, and finally the severest disease. And vaccinated immune systems are .