Cardiotoxicity of Non-Cardiovascular Drugs
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About this ebook
In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is paid to the preclinical screening of drug cardiotoxicity. Topics include:
- metabolic targets of cardiotoxicity
- regulatory aspects
- translating molecular mechanisms into clinical trials
- structure-activity relationships in arrhythmias by antihistamines and psychoactive drugs
- cardiovascular toxicity of antitumor drugs
- cardiovascular toxicities of non-steroidal anti-inflammatory drugs
- cardiovascular toxicities of antiretroviral therapies
Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.
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