Gene-editing offers hope for people with potentially fatal hereditary disorder

A breakthrough gene therapy could offer hope to people with a potentially fatal hereditary condition, new research suggests.

A single treatment of a gene-editing therapy has transformed the lives of a group of patients from the UK, New Zealand and the Netherlands who have hereditary angioedema.

The rare condition is characterised by severe, painful and unpredictable swelling attacks, which can interfere with daily life and can affect breathing.

Now researchers from the Cambridge University Hospitals, , and Amsterdam/Cas9, for which its inventors were awarded the in 2020.