NPR

Studying the link between the gut and mental health is personal for this scientist

Calliope Holingue researches how the microbiome and mind affect each other. She's part of a growing field, exploring how that connection could ultimately improve treatments for mental conditions.
Calliope Holingue is researching the microbiome among kids with autism. She's part of a growing field of research seeking to understand the gut-brain axis.

Sixteen years ago, when Calliope Holingue was in high school, she had a problem. Two, actually. She developed gastrointestinal symptoms severe enough to force her to give up running, plus she had a long history of anxiety and obsessive-compulsive disorder.

"And I wondered if maybe there was a link between my mental health and the GI symptoms I was experiencing," she recalls now.

Her doctors shrugged off her questions. "That led me to start reading a lot about the gut microbiome, the autonomic nervous system, and their connection with the brain and mental health," she says.

Today, Holingue has joined the ranks of scientists seeking to understand the interplay between the brain (and the rest of the nervous system) and the gut microbiome – that is the vast array of organisms, including bacteria, fungi and viruses, that thrive in the human gut.

She's now an assistant professor of mental health at the Johns Hopkins School of Public Health and part of the faculty at

You’re reading a preview, subscribe to read more.

More from NPR

NPR4 min read
What Took Him So Long? Colin Finally Likes Penelope Back In 'Bridgerton' Season 3
Bridgerton is many things — successful, uneven, entertaining — but it is, critically, obedient to the requirements of particular romance tropes. In the first season, when Daphne married Simon, that was a "fake relationship." In the second season, whe
NPR9 min read
How 'I Saw The TV Glow' Made A 'Teen Angst Classic' Soundtrack For The Ages
The newly released psychological horror film I Saw the TV Glow possesses a star-studded original soundtrack that stands on its own as a great, angsty album.
NPR2 min read
And The Winner Of The 2024 Tiny Desk Contest Is...
Nearly 7,000 independent artists submitted to this year's Tiny Desk Contest. Meet the Sacramento artist that rose to the top.

Related