Los Angeles Times

Sam Farmer's Week 2 NFL picks

Running back Saquon Barkley of the New York Giants runs the ball during the second half against the Tennessee Titans at Nissan Stadium on Sunday, Sept. 11, 2022, in Nashville, Tennessee.

The Los Angeles Times' NFL writer, Sam Farmer, examines this week's matchups. Lines according to FanDuel Sportsbook (O/U = over/under). Record last week: 10-5-1 (.667). Using point spreads with the scores Farmer predicted, the record against the spread last week would have been 9-7 (.563). All times Pacific.

Chargers (1-0) at Chiefs (1-0)

Thursday, 5:15 p.m.

Line: Chiefs by 4 1/2. O/U: 54 1/2.

Derwin James on Travis Kelce will be far more effective than anything the Cardinals did in the opener. That will free those pass rushers to zero in on Patrick Mahomes.

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