Posts About ‘Cross Reactants’ Misrepresent Accuracy of COVID-19 PCR Tests
SciCheck Digest
Polymerase chain reaction, or PCR, tests for COVID-19 are highly accurate. People on social media, however, are circulating lists of germs that they baselessly claim will cause such tests to be falsely positive. In reality, it’s the opposite. The lists include pathogens that have been tested by the manufacturers and did not react to the test.
Tests that detect current infections with SARS-CoV-2, the virus that causes COVID-19, are known as viral tests. There are two types: a Nucleic Acid Amplification Test, or NAAT, and an antigen test.
Many of the NAATs use a molecular biology technique known as the polymerase chain reaction, or PCR, to detect even a very tiny amount of the virus in a specimen.
The PCR test takes advantage of some natural features of biology to essentially scan through all of the RNA present in a sample — such as a nasal swab — and search for the presence of coronavirus RNA.
The Centers for Disease Control and Prevention NAATs “are unlikely to return a false-negative result of SARS-CoV-2,” and it recommends laboratory-based NAATS, the most sensitive
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